一、基本情况:
姓名:王炳锋
出生年月:1978年11月出生
性别:男
籍贯:广东
二、联系方式
地址:广州市天河区五山路483号英国威廉希尔公司 (510642)
E-mail:wbfeng@scau.edu.cn
WeChat: wbf3ng
知乎:https://www.zhihu.com/people/wbfeng
三、教育背景
1997/09-2001/06,华南师范大学化学系,化学教育,学士
2001/09-2004/06,华南师范大学化学系,物理化学,硕士
2015/09-2022/06,华南农业大学植保学院,农药学,博士
四、讲授课程:
本科生课程:《结构化学》《计算化学》《基础化学实验》
研究生课程:《化工产品多尺度模拟》,《智慧植保》
五、研究方向:
计算机辅助分子设计(小分子与生物大分子的互作模拟计算);
计算机辅助材料设计(电子结构计算);
机器学习(深度学习)在化学中的应用;
六、科研项目
1.基于MOFs纳米酶介导光热效应的免疫传感构筑及对食品中非法添加剂的识别研究(参与),国家自然科学基金项目,2022-09-07--2026-12-31
2.抗草地贪夜蛾轴手性吡唑靶向精准杀虫剂(参与),广州市科技计划项目,2020-04-01--2022-03-31
3. 双发射碳点比率荧光分子印迹传感器的构建及其对雪卡毒素的快速高灵敏检测(参与),面上项目,2020-02-24--2022-09-30
4.基于功能化二硫化钼构筑比率型免疫传感器对赭曲霉毒素广谱性识别的研究(参与),国家自然科学基金项目,2018-08-16--2022-12-31
5. 基于MALDI-TOFMS质谱成像的导向农药时空分布规律研究(参与),2018年以前广东省自然科学基金,2018-07-03--2020-12-31
6. 水稻病害图像识别模型(主持),国家重点研发计划子课题,2018-05-04--2020-12-31
7. 基于超分子作用的环糊精类导向农药载体的设计、合成及转运性能研究(参与),国家自然科学基金项目,2017-08-18--2020-12-31
8. 基于基因靶向切割的核酸扩增技术构建及其在马铃薯晚疫病检测中的应用(参与),国家自然科学基金项目,2017-08-18--2020-12-31
9. 印楝素抑制小菜蛾取食行为的中枢味觉环路机制研究(参与),2018年以前广东省自然科学基金,2017-06-27--2020-04-30
10. 水稻黄单胞杆菌CRISPR-Cas系统的功能鉴定与运用研究(参与),广州市科技计划项目,2017-01-14--2020-04-30
11.以植物氨基酸转运蛋白为载体的导向农药构建(主持),广州市科技计划项目,2017-01-01--2020-04-30
12. 基于α-氨基酸导向的异噁唑啉类农药的合成及其输导性(参与),国家自然科学基金项目,2016-08-17--2019-12-31
13. 利用3D打印技术制备高孔隙率载药材料的关键技术研究(参与),公益研究与能力建设,2016-04-22--2018-12-31
14. 功能化石墨烯分子印迹手性SPR传感器对手性氨基酸的识别及其机理研究(参与),国家自然科学基金项目,2015-08-19--2018-12-31
15. 乙醇、甘油水蒸汽重整制氢催化剂的改性及反应机理研究(参与),2018年以前广东省自然科学基金,2012-06-10--2014-10-01
16. 新型功能农膜的研发与产业化(参与),2014年以前项目,2011-11-22--
红、兰转光剂及转光膜的产业化生产及应用(参与),技术开发,2011-03-01--2012-03-30
17. 白光LED用新型卤硅酸盐荧光粉的研究(参与),青年人才培养计划(育苗计划),2010-07-01--2013-03-12
18. 新型靶向抗菌配合物的设计、合成及生物活性研究(参与),2018年以前广东省自然科学基金,2010-02-01--2012-10-01
19. 新型L-氨基酸-金属离子-苯并咪唑衍生物复合抗菌剂的研制及其应用(参与),2014年以前项目,2009-09-03--2012-06-30
20. 提升锂离子电池正极材料纳米级锂镍钴锰氧性能的研究(参与),2018年以前广东省自然科学基金,2006-08-17--2008-10-01
七、科研著作
1. Xu, Yue-Hua; Chen, Chao; Yang, Xue-Ling; Li, Xin; Wang, Bing-Feng; Preparation, characterization and photocatalytic activity of the neodymium-doped TiO2 nanotubes, Applied Surface Science, 2009, 255(20): 8624-8628. (期刊论文)
2. Liu Hua-Nai; Wang Bing-Feng; Sun Ming; Zhang Lei; Quantum chemistry calculation on 5'-pTpTpCp-3'cleavage by Serine/Histamine amide, CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2007, 28(8): 1566-1569. (期刊论文)
3. Zeng, MD*; Xu, X; Wang, BF; Wang, BC; Calculations of hyperpolarizabilities for para-disubstituted benzenes with the QSPR, Chinese Chemical Letters, 2004, 15(6): 753-756. (期刊论文)
4. Xu, Xiaoyan; Zhang, Yi; Wang, Bingfeng; Luo, Lin; Xu, Zhenlin; Tian, Xingguo*; A novel surface plasmon resonance sensor based on a functionalized graphene oxide/molecular-imprinted polymer composite for chiral recognition of l-tryptophan, RSC Advances, 2018, 8(57): 32538-32544. (期刊论文)
5. Gan, Cuifen; Wang, Bingfeng; Huang, Junying; Qileng, Aori; He, Zuyu; Lei, Hongtao; Liu, Weipeng*; Liu, Yingju*; Multiple amplified enzyme-free electrochemical immunosensor based on G-quadruplex/hemin functionalized mesoporous silica with redox-active intercalators for microcystin-LR detection, Biosensors and Bioelectronics, 2017, 98: 126-133. (期刊论文)
6. Shen, Fang; Liu, Ya-Xian; Li, Shu-Min; Jiang, Chi-Kun; Wang, Bing-Feng; Xiong, Ya-Hong*; Mao, Zong-Wan; Le, Xue-Yi*; Synthesis, crystal structures, molecular docking and in vitro cytotoxicity studies of two new copper(II) complexes: special emphasis on their binding to HSA, New Journal of Chemistry, 2017, 41(21): 12429-12441. (期刊论文)
7. 周琢强; 张艳虎; 蒋红霞; 杨晓云; 潘汝谦; 王炳锋; 一种2#巯基#4#取代#6#氟苯并噻唑及2#巯基衍生物的制法、应用, 2017-09-12, 中国, CN201710818603.6. (专利)
8. Shen, Fang; Ou, Zhi-Bin; Liu, Yu-Jia; Liu, Wei; Wang, Bing-Feng; Mao, Zong-Wan; Le, Xue-Yi*; Two Cu(II) complexes containing 2,4-diamino-6-(2-pyridy1)-1,3,5-triazine and amino acids: Synthesis, crystal structures, DNA/HSA binding, molecular docking, and in vitro cytotoxicity studies, Inorganica Chimica Acta, 2017, 465: 1-13. (期刊论文)
9. Mao, Gen-Lin; Yan, Yin; Chen, Yan; Wang, Bing-Feng; Xu, Fei-Fei; Zhang, Zhi-Xiang; Lin, Fei*; Xu, Han-Hong*; Family of Ricinus communis Monosaccharide Transporters and RcSTP1 in Promoting the Uptake of a Glucose Fipronil Conjugate, Journal of Agricultural and Food Chemistry, 2017, 65(30): 6169-6178. (期刊论文)
10.Zeng, Zhigang; Yan, Ying; Wang, Bingfeng; Liu, Niu; Xu, Hanhong*; Discovery and identification of O, O-diethyl O-(4-(5-phenyl-4,5-dihydroisoxazol-3-yl) phenyl) phosphorothioate (XP-1408) as a novel mode of action of organophosphorus insecticides, Scientific Reports, 2017, 7(1): 3617. (期刊论文)
11. Gan, Qian; Zhang, Chun-Lian; Wang, Bing-Feng*; Xiong, Ya-Hong; Fu, Yin-Lian; Mao, Zong-Wan; Le, Xue-Yi*; Two new mixed copper(II)-dipeptide complexes of N,N-donor heterocycle ligands: studies on their non-covalent DNA binding, chemical nuclease, antioxidant and anticancer activities, RSC Advances, 2016, 6(42): 35952-35965. (期刊论文)
12. Xu, Zhen Lin; Xie, Gui Mian; Li, Yong Xiang; Wang, Bing Feng; Beier, Ross C; Lei, Hong Tao; Wang, Hong; Shen, Yu Dong*; Sun, Yuan Ming; Production and characterization of a broad-specificity polyclonal antibody for O,O-diethyl organophosphorus pesticides and a quantitative structure-activity relationship study of antibody recognition, Analytica Chimica Acta, 2009, 647(1): 90-96. (期刊论文)
13.Yao, Guangkai; Wang, Bing-Feng; Yang, Shuai; Zhang, Zhi-Xiang; Xu, Han-Hong*; Tang, Ri-Yuan*; DMSO-mediated palladium-catalyzed cyclization of two isothiocyanates via C-H sulfurization: a new route to 2-aminobenzothiazoles, RSC Advances, 2019, 9(6): 3403-3406. (期刊论文)
14. Cai, Yue; Fang, Jingkun; Wang, Bingfeng; Zhang, Fangshuai; Shao, Guang*; Liu, Yingju*; A signal-on detection of organophosphorus pesticides by fluorescent probe based on aggregation-induced emission, Sensors and Actuators B: Chemical, 2019, 292: 156-163. (期刊论文)
15. 张燚; 王炳锋; 田兴国; 徐小艳*; 分子模拟法研究聚多巴胺与色氨酸的分子印迹手性识别机理, 华南农业大学学报, 2019, 40(06): 118-123. (期刊论文)
16. 王炳锋; 周海霞; 基于教育公平下的我国城市民办教育政策执行力的研究——以广州市民办教育为例, 江西化工, 2019, (04): 181-184. (期刊论文)
17.Cai, Jun; Wang, Bingfeng; Li, Jiadong; Chen, Zijian; Rao, Meifang; Muyldermans, Serge; Hua, Xiude; Xie, Xi; Wang, Hong*; Yang, Jinyi; Xu, Zhenlin; Shen, Yudong; Sun, Yuanming; Guided Evolution of Recombinant Bombyx mori Acetylcholinesterase II by Homology Modeling to Change Pesticide Sensitivity, International Journal of Molecular Sciences, 2018, 19(11): 3366. (期刊论文)
18. Wei, Yanan; Wang, Bingfeng; Cui, Xinfang; Muhammad, Yaseen; Zhang, Yanjuan; Huang, Zuqiang; Li, Xuesheng; Zhao, Zhenxia; Zhao, Zhongxing; Highly Advanced Degradation of Thiamethoxam by Synergistic Chemisorption-Catalysis Strategy Using MIL(Fe)/Fe-SPC Composites with Ultrasonic Irradiation, ACS Applied Materials & Interfaces, 2018, 10(41): 35260-35272. (期刊论文)
19.Chen, Zi-Jian; Zhang, Xuan; Wang, Bing-Feng; Rao, Mei-Fang; Wang, Hong; Lei, Hong-Tao*; Liu, Hui; Zhang, Yan; Sun, Yuan-Ming; Xu, Zhen-Lin*; Production of Antigen-Binding Fragment against O,O-Diethyl Organophosphorus Pesticides and Molecular Dynamics Simulations of Antibody Recognition, International Journal of Molecular Sciences, 2018, 19(5): 1381. (期刊论文)
20. Zhu, Meiping; Muhammad, Yaseen; Hu, Peng; Wang, Bingfeng; Wu, Yang; Sun, Xiaodan; Tong, Zhangfa; Zhao, Zhenxia*; Enhanced interfacial contact of dopamine bridged melamine-graphene/TiO2 nano-capsules for efficient photocatalytic degradation of gaseous formaldehyde, Applied Catalysis B: Environmental, 2018, 232: 182-193. (期刊论文)
21.Luo, Zijie; Liu, Bin*; Zhu, Kangning; Huang, Yingying; Pan, Chengjun; Wang, Bingfeng*; Wang, Lei*; An environment-sensitive fluorescent probe for quantification of human serum albumin: Design, sensing mechanism, and its application in clinical diagnosis of hypoalbuminemia, Dyes and Pigments, 2018, 152: 60-66. (期刊论文)
22. Zhang, Zhao-Sheng; Huang, Yun-Zhen; Luo, Jian; Wang, Bing-Feng; Jin, Zhen; Liu, Ya-Hong; Tang, You-Zhi*; Synthesis and Antibacterial Activity Against MRSA of Pleuromutilin Derivatives Possessing a Mercaptoethylamine Linker, Medicinal Chemistry, 2018, 14(6): 585-594. (期刊论文)
23. 陈功; 武煜翔; 卢真保; 王炳锋; 杨东晓; 赵钟兴*; 黄艳*; 苯乙醇和茴香醚在含Fe蚕沙基生物碳材料的储香与释放性能研究, 化工学报, 2020, 71(12): 5628-5635. (期刊论文)
24. 彭红星; 李泽轩; 钟景润; 王炳锋; 谢芷华; 谢宇笙; 李世煖; 一种水稻病虫害识别方法和系统, 2020-08-13, 中国专利, ZL202010811336.1. (专利)
25. 彭红星; 李世煖; 田兴国; 冼继东; 吕建秋; 王炳锋; 陈虎; 何慧君; 徐慧明; 谢芷华; 一种农作物虫害检测方法及系统, 2021-02-23, 中国专利, ZL202110199295.X. (专利)
26. Guo, Yan; Jin, Yulong*; Wang, Bingfeng; Liu, Boping*; Molecular Mechanism of Small-Molecule Inhibitors in Blocking the PD-1/PD-L1 Pathway through PD-L1 Dimerization, International Journal of Molecular Sciences, 2021, 22(9): 4766. (期刊论文)
27.Wang, Bingfeng; Yang, Chen; Jiang, Xunyuan; Wen, Yingjie; Tian, Yongqing; Zhao, Chen*; Xu, Hanhong*; Design of new glycosyl-O-fipronil conjugates with improved hydrolysis efficiency assisted by molecular simulations, Pest Management Science, 2022, 78(6): 2667-2678. (期刊论文)
28.Wu, Xiaoyan; Wang, Na; Liang, Jianhuai; Wang, Bingfeng; Jin, Yulong; Liu, Boping*; Yang, Yang*; Is the Triggering of PD-L1 Dimerization a Potential Mechanism for Food-Derived Small Molecules in Cancer Immunotherapy? A Study by Molecular Dynamics, International Journal of Molecular Sciences, 2023, 24(2): 1413. (期刊论文)
29.Jia, Tianhao; Pu, Chunmei; Qin, Tianyi*; Liu, Bin; Yao, Guangkai; Xun, Zhiqing; Wang, Bingfeng; Tian, Yongqing; Zhang, Zhixiang*; Xu, Hanhong*; Zhao, Chen*; Azocalixarene-Based Supramolecular System for the Detection of Paraquat via an Improved Indicator Displacement Assay, Journal of Agricultural and Food Chemistry, 2022, 70(50): 15981-15989. (期刊论文)
30. Liang, Jianhuai; Wang, Bingfeng; Yang, Yang; Liu, Boping*; Jin, Yulong*; Approaching the Dimerization Mechanism of Small Molecule Inhibitors Targeting PD-L1 with Molecular Simulation, International Journal of Molecular Sciences, 2023, 24(2): 1280. (期刊论文)
31.Zhu, Hongshuai; Wang, Bingfeng; Liu, Yingju*; Coordinating Etching Inspired Synthesis of Fe(OH)3 Nanocages as Mimetic Peroxidase for Fluorescent and Colorimetric Self-Tuning Detection of Ochratoxin A, Biosensors-Basel, 2023, 13(6): 665. (期刊论文)
32.Chen, Dongping; Li, Kang; Wang, Bingfeng; Chen, Huimin; Jiang, Heng; Zhao, Chen; Yao, Guangkai; Li, Sheng*; Xu, Hanhong*; Bruceine D Acts as a Potential Insecticide by Antagonizing 20E-EcR/USP Signal Transduction, Journal of Agricultural and Food Chemistry, 2023, 71(30): 11491-11501. (期刊论文)